Repositori BKPKPenggunaan Mencit untuk Pemeriksaan Potensi Toksoid DifteriMuljatiPrijantoauthorAt present, the potency test of diphtheria toxoid is carried out on guines pigs as experimental animals. Production of a large number of guinea pigs suitable for experiment is still considered to be a substantial problem, especially in some developing countries, due to economical and enviromental difficulties of the breeding and maintenance of the animals. The antibody induction (A.I.) assays in mice instead of guinea pigs, for testing the potency of diphtheria toxoid were carried out in this study. The neutralizing antibody levels in the sera from immunized mice were measured by cell culture method using vero cells. The results of 7 batches of DPT and DT vaccines obtained by AI best in mice were correlated significantly with the lethal challenge test in guinea pigs. More data are still required to confirm this observation, before the test can be applied routinely.WC 195-425 Infection. Bacterial Infections1987Badan Penelitian dan Pengembangan KesehatanArticle

For work being deposited by its own author: In self-archiving this collection of files and associated bibliographic metadata, I grant Repositori BKPK the right to store them and to make them permanently available publicly for free on-line. I declare that this material is my own intellectual property and I understand that Repositori BKPK does not assume any responsibility if there is any breach of copyright in distributing these files or metadata. (All authors are urged to prominently assert their copyright on the title page of their work.)

For work being deposited by someone other than its author: I hereby declare that the collection of files and associated bibliographic metadata that I am archiving at Repositori BKPK is in the public domain. If this is not the case, I accept full responsibility for any breach of copyright that distributing these files or metadata may entail.

Clicking on the Deposit Item Now button indicates your agreement to these terms.