<mets:mets OBJID="eprint_1368" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-05T23:48:28Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_1368_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>Uji Aktivitas Ekstrak Etanol 50% Umbi Keladi Tikus (Typhonium Flagelliforme (LOOD) BI) Terhadap Sel Kanker Payudara MCF-7 In Vitro</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Lucie</mods:namePart><mods:namePart type="family">Widowati</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Harfia</mods:namePart><mods:namePart type="family">Mudahar</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Keladi tikus root (Typhonium flagelliforme (Lodd) BI) is one of plants that is used for cancer healing. The plant contents flavonoid, tannin, terpenoid and steroid. Flavonoid and terpenoid compound groups are known for anti cancer activities.      The investigation is conducted to test cytotoxic effect of ethanol free dry extract of keladi tikus root (Typhonium flagelliforme (Lood)BI) against brest cancer cell MCF-7. Maceration extraction method used 50% ethanol solvent and vaporized until ethanol free dry extract of keladi tikus root was obtained. The test used 5 level of concentration, those were 50, 75, 100, 125 and 150  ug/ml with 3 times iteration. DMSO was used as negative control and Cisplatin with concentration of 4, 6, 8, 19, 12 ug/ml were used as positive control. Test result showed ethanol free dry extract of keladi tikus root has value of LC50  = 89,15 and Cisplatin has value of LC50  = 7,84 ug/ml .Further investigation of advance sitotoxic test value LC50  and value LC50  against fraction of 50% ethanol extract is necessary to obtain active compound against brest cancer cell MCF-7.</mods:abstract><mods:classification authority="lcc">QY 50-110 Laboratory Animals. Laboratory Techniques</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">2009</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Badan Penelitian dan Pengembangan Kesehatan</mods:publisher></mods:originInfo><mods:genre>Article</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_1368"><mets:rightsMD ID="rights_eprint_1368_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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