<mets:mets OBJID="eprint_2487" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-05T15:01:56Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_2487_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>PEMBUATAN ANTIBODI MONOKLONAL TERHADAP B. PERTUSSIS UNTUK PENGAMBANGAN DIAGNOSA BATUK REJAN</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Rini</mods:namePart><mods:namePart type="family">Pangastuti</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Muljati</mods:namePart><mods:namePart type="family">Prijaanto</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Dyah</mods:namePart><mods:namePart type="family">Isbagio</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Eko</mods:namePart><mods:namePart type="family">Suprijanto</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Produksi antibodi monoklonal terhadap fraksi kuman Bordetella pertussis yaitu Filamentous Hemagglutinin (FHA), telah dilakukan di laboratorium Puslit Penyakit Menular, Badan Penelitian dan Pengembangan Kesehatan, DepKes RI, menggunakan penerapan biotehnologi.        Telah dilakukan fusi antara sel mieloma line PX63 Ag6.8.5.3 yang pada pembiakannya menggunakan mencit strain Balb/C dengan sel B.limfosit yang diperoleh dari limfa mencit strain Balb/C yang sebelumnya telah diimunisasi dengan antigen FHA. Inducer yang digunakan adalah PEG 4000 pada konsentrasi 50% b/v.        Sasaran yang hendak dicapai dengan antibodi monoklonal ini adalah pengembangan imunodiagnosa infeksi batuk rejan yang spesifik, mudah, cepat dan dapat mengurangi kerancuan diagnosa laboratorisnya terhadap infeksi saluran pernapasan atas lain.        Apabila diagnosa batuk rejan dapat ditegakkan lebih dini, diharapkan dapat menunjang Program Pengembangan Imunisasi dan Survailans dari penyakit yang dapat dicegah Dengan Imunisasi di Indonesia.</mods:abstract><mods:classification authority="lcc">QW 1-300 Microbiology</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">1991</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Puslit Penyakit Menular</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_2487"><mets:rightsMD ID="rights_eprint_2487_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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