<mets:mets OBJID="eprint_2714" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-04T01:56:24Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_2714_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>PENELITIAN RUTIN PENGUKURAN NILAI KOMPOSISI DARAH MENCIT SEBAGAI STANDAR UNTUK PENELITIAN YANG MENGGUNAKAN MENCIT SEBAGAI HEWAN PERCOBAAN</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Rita Marleta</mods:namePart><mods:namePart type="family">Dewi</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Emiliana</mods:namePart><mods:namePart type="family">Tjitra</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Marvel</mods:namePart><mods:namePart type="family">Renny</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Rabea P.</mods:namePart><mods:namePart type="family">Yekti</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Dilakukan pemeriksaan terhadap mencit normal strain Swiss Derived dan BALB/c yang dikelompokkan berdasarkan jenis kelamin (jantan dan betina) dan umur (3 minggu dan 6 minggu). Pemeriksaan terdiri dari pemeriksaan darah rutin dan kimia darah. Selanjutnya pelaksanaan dikembangkan dengan melakukan uji coba infeksi Plasmodium berghei sebanyak 10 pangkat 4 dalam 0,1 cc darah pada mencit strain Swiss, jantan, umur 6 minggu untuk mengetahui perubahan keadaan komposisi darah mencit yang disebabkan oleh malaria tersebut.      Pada penelitian ini ternyata jika dibandingkan dengan hasil penelitian Mitruka, normal mencit disini mempunyai nilai rata-rata lebih rendah pada darah rutin (eritrosit dan leukosit), lebih tinggi pada kimia darah (kolesterol, ureum, glukosa, fosfatase alkali, SGPT dan SGOT) sedangkan hemoglobin, hematokrit, trombosit, hitung jenis, bilirubin, total protein dan kreatinin relatif sama.      P.berghei pada penelitian ini terutama menyebabkan anemia hemolitik. Semakin lama infeksi, anemia semakin berat, sedangkan perubahan kimia darah sesuai dengan angka kepadatan parasit.</mods:abstract><mods:classification authority="lcc">QY 50-110 Laboratory Animals. Laboratory Techniques</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">1993</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Puslit Penyakit Menular</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_2714"><mets:rightsMD ID="rights_eprint_2714_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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