<mets:mets OBJID="eprint_3032" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-05T21:15:16Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_3032_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>Pengembangan Diagnosis Sampel Demam Berdarah : Deteksi dan Karakteristik Genetik Virus Sampel Sistem Sentinel Surveilans Dengue Sebagai Data Dasar (Laporan Penelitian)</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Reni</mods:namePart><mods:namePart type="family">Herman</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Masri</mods:namePart><mods:namePart type="family">Maha</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Rabea Pangesti</mods:namePart><mods:namePart type="family">Yekti</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Virus Dengue terdiri dari 4 serotipe, masing-masing serotipe masih terdapat beberapa tipe lagi berdasarkan gen selubung virus. Spesimen serum dikirim dari RSUD Deli Serdang, RSUD Balikpapan, RSUD Wonosari, RSUD Bitung, RSUD Haulussy Ambon dan RSU Prov. NTB di Mataram. Spesimen dengan volum mencukupi diidentifikasi serotipe virus menggunakan metode RT-PCR. Sampel positif dilanjutkan dengan deteksi genotipe virus berdasarkan gen selubung virus menggunakan primer spesifik. Hasil Pemeriksaan  sekuensing dianalisis dengan perangkat lunak MEGA 6 untuk membuat pohon filogenetik guna pengelompokkan genotipe berdasarkan gen referens. Enam ratus lima puluh lima spesimen memenuhi syarat untuk dilakukan pemeriksaan, dari 687 spesimen terkumpul. Sebanyak 50,7 % diantaranya positif. Jumlah paling banyak adalah virus dengue serotipe 3 (DENV-3), yaitu 52 % dari keempat serotipe. Sementara DENV-2, DENV-1 dan DENV-4 masing-masing 21, 18 dan 9%. Hasil pemeriksaan genetik menunjukan DENV-1 termasuk ke dalam kelompok genotipe I. Sementara DENV-4 belum berhasil diidentifikasi genotipe pada penelitian ini. Selain itu, 6 spesimen positif virus chikungunya dari 410 spesimen yang dideteksi. Lima spesimen berasal dari Ambon dan 1 spesimen berasal dari Deli Serdang. Tidak ada spesimen yang terindentifikasi flavivirus lainnya.</mods:abstract><mods:classification authority="lcc">WC 500-590 Virus Diseases</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">2016</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Pusat Penelitian dan Pengembangan Upaya Kesehatan Masyarakat</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_3032"><mets:rightsMD ID="rights_eprint_3032_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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