Repositori BKPKLaporan Penelitian Daya Antipiretik dan Keamanan Ekstrak Alstonia Scholaris R. Br. 1982-1983NaniSukasediatiauthorBambangWahjoediauthorJanaharMuradauthorSutjiptoSutjiptoauthorRebusan (infus) kulit kayu Alstonia R.Br. (pule) digunakan oleh masyarakat dan sudah dibuktikan pada hewan percobaan sebagai obat anti demam. Untuk lebih memudahkan penggunaan, dirasa perlu mencari bentuk sediaan yang lebih praktis. Pada penelitian ini dicari ekstrak yang paling mendekati infus, dibuktikan daya antipiretiknya, diperiksa toksisitasnya akut maupun kronis, kemudian dicari bentuk sediaannya yang paling sesuai. Dari 6 (enam) ekstraksi, ternyata ekstraksi menggunakan alkohol 50% paling mendekati infus, dan ekstrak tersebut termasuk kategori "Practically Non Toxic".QV 701-835 Pharmacy and Pharmaceutics1983Pusat Penelitian FarmasiMonograph

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