Repositori BKPKLaporan Uji Manfaat dan Toksisitas Tanaman Obat 1987/1988BambangWahjoediauthorNurendah P.SubanuauthorLucieWidowatiauthorTelah dilakukan percobaan untuk menguji manfaat analgesik (mengurangi rasa sakit) dari 3 tanaman obat (Ruta angustifolia Pers., Urena lobata L., dan Baeckea frutescens L.) menurut cara Siegmund. Juga dilakukan percobaan toksisitas akut (LD-50) dari 3 tanaman obat lainnya (Curcuma aeruginosa Roxb., Curcuma heyneana Val., Brucea sumatrana Roxb.) menurut cara Weil C.S. Ke enam tanaman obat tersebut di atas diperoleh dari Balai Penelitian Tanaman Obat Tawangmangu, Surakarta dan diolah menjadi infus menurut cara Farmakope Indonesia. Hasil percobaan menunjukkan bahwa hanya daun Ruta angustifolia Pers. sampai dengan dosis 80 mg menunjukkan efek mengurangi rasa sakit, sedangkan Curcuma heyneana Val. dan Curcuma aeruginosa Roxb. menurut kriteria Gleason termasuk Practically Non Toxic sedang Brucea sumatrana Roxb. termasuk bahan yang toksik.QV 701-835 Pharmacy and Pharmaceutics1988Pusat Penelitian dan Pengembangan FarmasiMonograph

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