<mets:mets OBJID="eprint_4073" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-04T12:17:24Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_4073_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>Laporan Akhir Penelitian Pengaruh Ekstrak Physalis Minima L. dan Costus Speciosus Smith Terhadap Organ Reproduksi Tikus Yang Diovarektomi Serta Toksisitasnya Akutnya</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Sa'roni</mods:namePart><mods:namePart type="family">Sa'roni</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Herba Phyadus minima L (Cecendet) dan akar Costus speciosus smith (pacing) diantaranya mengandung steroid. Mungkin Steroid yang dikandung mempunyai efek estrogenik sehingga dapat mencengah atau mengembalikan uterus yang mengalami atrofi akibat ovarektomi. Oleh karena itu dilakukan penelitian pengaruh ekstrak herba Physalis minima L dan akar  Costus speciosus Smith terhadap organ reproduksi tikus yang diovarektomi menurut Fasrasworth et al. Untuk menentukan besarnya dosis penelitian serta kesamaan pemakaian dilakukan pula penelitian toksisitas akut bahan menurut cara Weil.CS.&#13;
Hasil penelitian meunjukkan bahwa ekstrak alkohol 75%, herba Physalis minima L. dan akar Costus speciosus Smith termasuk bahan yang tidak toksik dan mempunyai pengaruh terhadap &#13;
susunan syaraf pusat maupun susunan syaraf otonum. Ekstrak a1kohol 75% herba Physalis minima L.dosis 0,91 mg dan 9,1 mg/100 g bobot badan dapat mencegah atrofi  uterus  pada tikus yang diovarektomi. Pada dosis 91 mg/100 g bobot badan efeknya berkurang. Ekstrak akar Costus speciosus Smith  dosis  116,7 mg /100  g bobot badan  menunjukan ·adanya indikasi pencegahan/pengembalian atrofi uterus pada tikus  yang diovareh1omi. Pada dosis penelitian  yang lebih rendah tidak menunjukan efek.</mods:abstract><mods:classification authority="lcc">W 1-28 Reference Works. General Works</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">1994</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Pusat Penelitian dan Pengembangan Farmasi</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_4073"><mets:rightsMD ID="rights_eprint_4073_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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