<mets:mets OBJID="eprint_4075" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-05T16:40:50Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_4075_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>Laporan Penelitian Pengaruh Ekstrak Physalis Minima L. dan Costus Speciosus Smith. Terhadap Organ Reproduksi Tikus Yang Diovarektomi</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Sa'roni</mods:namePart><mods:namePart type="family">Sa'roni</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Telah dilakukan penelitian pengaruh ekstrak herba Physalis minima L dan akar Costus speciosus Smith dalam etanol 75% secara percolasi terhadap organ reproduksi tikus yang diovarektomi menurut Farnsworth et al. Untuk menentukan dosis penelitian serta keamanan pemakaian dilakukan penelitian tobisitas akut terhadap kedua ekstrak tanaman menurut cara Weil,C.S.&#13;
Menurut beberapa penelitian herba Physalis minima L ( cecendet ) dan akar Costus speciosus Smith ( pacing ) mengandung steroid yang dikatakan mempunyai efek estrogenik sehingga dapat mencegah atau mengembalikan uterus yang mengalami atrofi akibat ovarekiomi.&#13;
Hasil penelitian menunjukkan bahwa ekstrak herba Physalis minima L dan akar Costus speciosus Smith termasuk bahan yang tidak toksik dan mempunyai pengaruh terhadap susunan&#13;
syaraf pusat maupun susunan syaraf otomun.&#13;
Analisa ANOVA pengaruh bahan terhadap uterus tikus yang diovarektomi menunjukkan ada perbedaan yang nyata diantara perlakuan. Ekstrak etanol 75% herba Physalis minima L. dosis 0,91 mg dan 9,1 mg/100 g bobot badan dapat mencegah atrofi uterus pada tikus yang diovarek1omi. Pada dosis 91 mg/100 g bobot badan efekya berkurang ( P= 0,01). Ekstrak akar Costus speciosus &#13;
Smith do sis 116,7 mg /100 g bobot badan memmjukan adanya indikasi pencegahan /pengembalian&#13;
atrofi uterus pada tikus yang diovarektomi. Pada dosis penelitian yang lebih rendah tidak&#13;
menunjukan efek ( P = 0,05).</mods:abstract><mods:classification authority="lcc">QV 701-835 Pharmacy and Pharmaceutics</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">1994</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Pusat  Penelitian dan Pengembangan Farmasi</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_4075"><mets:rightsMD ID="rights_eprint_4075_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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