<mets:mets OBJID="eprint_5710" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-05T12:01:02Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_5710_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>FLUKTUASI KADAR TSH DAN FREE T4 SELAMA SUPLEMENTASI SPIRULINA&#13;
SEBAGAI SUMBER IODIUM ALAMI PADA WANITA USIA SUBUR&#13;
DI DAERAH ENDEMIK GAKI</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Sri</mods:namePart><mods:namePart type="family">Nuryani Wahyuningrum</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">R.</mods:namePart><mods:namePart type="family">Agus Wibowo</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:name type="personal"><mods:namePart type="given">Taufiq</mods:namePart><mods:namePart type="family">Hidayat</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Spirulina merupakan mikroalga berasal dari laut yang berpotensi menjadi sumber iodium alami&#13;
dengan kandungan iodium sebesar 94,5 ppm. Tujuan dari penelitian ini adalah untuk mengetahui&#13;
pengaruh konsumsi spirulina terhadap kadar TSH dan fT4 pada wanita usia subur yang beresiko&#13;
hipotiroid. Jenis penelitian adalah Randomized Control Trial (RCT) double blind. Subyek&#13;
penelitian adalah Wanita Usia Subur (WUS) usia 18 - 40 tahun, mempunyai kadar TSH 3-6,2&#13;
μIU/L, dibagi menjadi 2 kelompok. Kelompok kontrol diberi plasebo dan kelompok perlakuan&#13;
diberi spirulina, sebanyak 1 gr/hr, selama 3 bulan. Spirulina dan plasebo dikemas dalam bentuk&#13;
kapsul yang serupa. Kadar TSH dan fT4 dianalisis dengan metode ELISA dari sampel serum&#13;
darah subyek. Darah subyek diambil dari pembuluh vena lengan sebanyak 2 cc. Hasil penelitian&#13;
menunjukkan bahwa pemberian spirulina tidak mempengaruhi kadar TSH (P &gt; 0,05), namun&#13;
dapat meningkatkan kadar hormon tiroid fT4 lebih tinggi dibandingkan kelompok kontrol (P &lt;&#13;
0,05). Spirulina bisa menjadi alternatif sumber iodium selain garam untuk meningkatkan fungsi&#13;
tiroid.</mods:abstract><mods:classification authority="lcc">QV Pharmacology</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">2015-03</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Badan Penelitian dan Pengembangan Kesehatan</mods:publisher></mods:originInfo><mods:genre>Article</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_5710"><mets:rightsMD ID="rights_eprint_5710_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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