<mets:mets OBJID="eprint_61" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-05T11:16:59Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_61_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>Dampak Imunisasi Hepatitis Rekombinan terhadap Penularan Vertikal Virus Hepatitis B pada Bayi di Kota Bandung, Jawa Barat</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Djoko</mods:namePart><mods:namePart type="family">Yuwono</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Telah diteliti tentang dampak imunisasi Hepatitis B menggunakan vaksin Hepatitis B rekombinan di Kota Madya Bandung, Propinsi Jawa Barat. Subyek penelitian sebanyak 186 ibu hamil trimester III dan 152 bayi yang dilahirkan.  Imunisasi Hepatitis B menggunakan vaksin Hepatitis B rekombinan buatan PT. Bio Farma Bandung, dilakukan oleh petugas kesehatan setempat dengan strategi imunisasi sesuai dengan Pengembangan Program Imunisasi (PPI) selama ini yaitu pada bulan ke 0-2 dan bulan ke 4-7. Pemeriksaan seromarker Hepatitis B diakukan terhadap serum ibu hamil; tali pusat bayi dan darah vena bayi yang dilahirkan pasca imunisasi. Pemeriksaan dilakukan terhadap seromarker HbsAg; Anti HBc dan anti HBs menggunakan ELISA kit diagnosa  produksi ABBOTT Murex, United Kingdom.  Hasil penelitian menunjukkan bahwa ditemukan prevalensi HbsAg dan HBcAg masing-masing sebesar 5,1% ditemukan juga 2,6% anti HBc pada ibu hamil. Selain itu ditemukan juga adanya trasnmisi vertikal Virus Hepatitis B (VHB) sebesar 5,9% di Kota Madya Bandung. Pemberian imunisasi Hepatitis B rekombinan dapat menurunkan transmisi vertikal VHB (HbsAg) dari 7,2% menjadi 3,94% atau sebesar 45,4%. Diketahui pula imunogenitas vaksin karier VHB saja, sedangkan pada bayi lahir dari ibu karier dan non karies ditemukan imunogenitas vaksin Hepatitis B rekombinan sebesar 63,2%.</mods:abstract><mods:classification authority="lcc">QW 1-300 Microbiology</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">2000</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Pusat Penelitian dan Pengembangan Pemberantasan Penyakit</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_61"><mets:rightsMD ID="rights_eprint_61_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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