<mets:mets OBJID="eprint_63" LABEL="Eprints Item" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-3.xsd" xmlns:mets="http://www.loc.gov/METS/" xmlns:mods="http://www.loc.gov/mods/v3" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><mets:metsHdr CREATEDATE="2026-07-06T01:12:46Z"><mets:agent ROLE="CUSTODIAN" TYPE="ORGANIZATION"><mets:name>Repositori BKPK</mets:name></mets:agent></mets:metsHdr><mets:dmdSec ID="DMD_eprint_63_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:titleInfo><mods:title>Deteksi Interleukin-12 pada Respon Imun Selular terhadap Beberapa Jenis Antigen Campak untuk Menentukkan Tingkat Imunogenik Antigen</mods:title></mods:titleInfo><mods:name type="personal"><mods:namePart type="given">Djoko</mods:namePart><mods:namePart type="family">Yuwono</mods:namePart><mods:role><mods:roleTerm type="text">author</mods:roleTerm></mods:role></mods:name><mods:abstract>Pada respon imun seluler campak terjadi imunosepuresi sintesa IL-12 oleh makrofag. Akibat pada imunisasi campak respon humoralnya meningkat sedangkan respon selularnya menurun.  Hal ini diduga merupakan penyebab terjadinya kegagalan imunisasi campak di beberapa negara yang telah mencapai cakupan imunisasi lebih dari 100%.  Penelitian ini merupakan suatu uji in vitro terhadap empat jenis antigen campak yang selama ini digunakan di banyak negara termasuk di Indonesia yaitu : vaksin campak Schward, CAM-70 dan MMR (meales, mumps, rubella) dan AIK-C. Penelitian ini bertujuan mengembangkan sarana untuk menentukan perlunya dilakukan pemeriksaan IL-12 pada vaksin campak di masa datang.  Drai 35 sampel yang diperiksa diketahui bahwa ditemukan prosentase IL-12 sebesar 75%;73%;85%;72% dan 97%, masing-masing setelah secara in vitro mendapat stimulasi vaksin campak Schward;CAM-70;MMR;AIK-C dan kontrol antigen LPS.</mods:abstract><mods:classification authority="lcc">WC 500-590 Virus Diseases</mods:classification><mods:originInfo><mods:dateIssued encoding="iso8601">1998</mods:dateIssued></mods:originInfo><mods:originInfo><mods:publisher>Pusat Penelitian dan Pengembangan Pemberantasan Penyakit</mods:publisher></mods:originInfo><mods:genre>Monograph</mods:genre></mets:xmlData></mets:mdWrap></mets:dmdSec><mets:amdSec ID="TMD_eprint_63"><mets:rightsMD ID="rights_eprint_63_mods"><mets:mdWrap MDTYPE="MODS"><mets:xmlData><mods:useAndReproduction>
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