Repositori BKPKPenelitian Toksisitas Akut Natrium Nitrit pada Hewan Uji TikusSriEndreswariauthorThe acute toxicity of sodium nitrite in the period of observation for 14 days has been carried out on adult male and female rats. The substance was administered orally in the form of solution in distilled water. Each animal was observed carefully for six hours after administration, continued twice daily for 14 days, those including general appearance, body weight changes, signs of toxicity mortality and gross pathology finding. The signs of toxicity were tremor, ataxia and convulsion; mortalities were occurred in about two hours after administration. Some animal recovered after two-four hours. The LD50 in male mice was 121 (86,6 oo 169,4) mg/kg b.w, in female was 116 (86 oo 155,4) mg/kg b.w. Based on the LD50 value, sodium nitrite is classified as moderately toxic substances.QY 50-110 Laboratory Animals. Laboratory Techniques2000Badan Penelitian dan Pengembangan KesehatanArticle

For work being deposited by its own author: In self-archiving this collection of files and associated bibliographic metadata, I grant Repositori BKPK the right to store them and to make them permanently available publicly for free on-line. I declare that this material is my own intellectual property and I understand that Repositori BKPK does not assume any responsibility if there is any breach of copyright in distributing these files or metadata. (All authors are urged to prominently assert their copyright on the title page of their work.)

For work being deposited by someone other than its author: I hereby declare that the collection of files and associated bibliographic metadata that I am archiving at Repositori BKPK is in the public domain. If this is not the case, I accept full responsibility for any breach of copyright that distributing these files or metadata may entail.

Clicking on the Deposit Item Now button indicates your agreement to these terms.