ABSTRACT Antidiabetic use on renal disturbance patients need to applicate principal of clinical pharmacokinetics. Decreasing renal function could distrub excretion drug and increase accumulation drug within the plasma, therefore, toxic effect will be produced and it need to adjust dose. This research aimed at studying of clinical pharmacokinetic of oral antidiabetics on diabetes mellitus (DM) …
Having high quality of life is a challenge for school-age children (6-12 years old) who suffer from cancer. They have to undergo cancer treatments that bring pain and negative side-effects for years Repeated hospitalization also separates them from family and school, the essential contexts in school-age children development. By using qualitative approach with interview and observation, this re…
Role of EPCs on angiogenesis is impaired in diabetes. Study was design ed to investigate effect of vitamin E to ward ability of high glucose (HG) stimulated EPCs to release NO and inducemigration ofendothelial cells. Mononuclear cells were isolated from healthy subjects. After 7 days of culture, EPCs were cultured in 5 mM normal glucose in the absence or presence of 22 µM or 50 µM vitamin E, …
Current management of schizophrenia emphasizes on eclectic approach using bio-psychosocial theories. In conjunction with the standard anti-psychotic terapy, the eclectic counseling is thought to enhance clinical outcomes of patients with schizophrenia, by accelerating adaptive capacity recovery that allows normal function of the patients in the society. This study aimed to determine the effect…