Transforming Growth Factor-Beta 1 (TGF-β1) menjadi perantara fibrosis interstisial, atrofi tubular, dan kerusakan gromelurus ginjal. Proteinuria menunjukkan prognosis yang buruk pada sindroma nefrotik. Terdapat kecenderungan persisten proteinuria pada sindroma nefrotik resisten steroid. Tujuan penelitian ini untuk membuktikan hubungan kadar Transforming Growth Factor-Beta 1 (TGF-�…
Erre radicals in cigarette smoke was known could promote infertility. Fee radicals activity can be inhibited by antioxidant in black seed (thymoquinane, nogelllone, carvvacrol, t-anethole, and 4 terpineol). The aim of this study was to assess the effect of black seed extract on MDA concentration in testis and spermatogonium cell number in subacute nonfilter-tipped cigarette smoke exposed rats. …
Glucocorticoid receptors (GR) have an important role in the resistance of steroid of steroid therapy. Previous studies showed significant difference activation and expression of GR between Steroid Resistant Naphrotic Syndrome (SRNS) and Steroid Sensitive Nephrotic Syndrome (SSNS), however the other studies showwed contrastive result. Previous studies also revealed Hsp-90 had an important role i…
A six year-old Indonesian boy attended the outpatient clinic of the Dr. Soetomo Hospital on May 30, 1995 with the main complaint of weakness manifesting in an awkward gait since 3 years. Growth and development were abnormal. His aunt had a similar illnes; his mother, father, grandmother and grandfather were healthy. Physical examination revealed : a weak boy with a body weight of 14.5 kg and a …