Multiple myeloma (MM) is a neoplasm of mature and immature plasma cells. The clinical manifestation of this disorder results from the uncontrolled and progressive proliferattion of these cells, the effect of marrow replacement, and the over production of M-component. The incidence is varies and rise with age. In the last five years, in Hasan Sadikin Hospital-Bandung, we found thirty seven cases…
Myelotoxicity secondary to treatment of malignancies with chemotherapy/radiation therapy gives rise to infection which can be fatal. GM-CSF is a hemopoeitic growth factor that regulates growth and function of granulocytes (neutrophyl and eosinophyl), and monocytes/macrophages. Four hundred u micrograms of GM-CSF (leucomax) is given subcutaneously in five consecutive days to eight cases of acute…
A multicenter, clinical trial, randomized open label and parallel study has been done since April 1993 on the Chronic Myelogenous Leukemia patients treated with either Interferon (I) + Hydroxyurea (HU) or Interferon + low dose Ara-C (C). The countries who involve on this study are Indonesia, China, India, Philippines, Singapore, South Korea and Taiwan. The dose of Interferon is 5 MU 5 days a we…