The increased percentage of patients with HIV-TB coinfection leads to inevitable interactions between rifapincin and efavirenz Efavirenz is a potent non-nucoside reverse transcripate inhibitor (NNRT) for the treatment of HIV infection. The use of this drug combination with rifampicin causes problem in determination of the optiml dosage of efavirenz when adminstered concomitanly with refapicin.E…
The molecular mechanisms responsible for electronechanical derangements found in primary left venticular (LV) hypertrophy have not been clearly elucidated Of particular is the interest is the voltage gated L-type Ca curreent (Ica1) which plays crucial role in the EC-coupling. This study aimed to investigate cardiomuocyte Ica(1) in newly developed lime of rats namely HHR (hypertrophy have not be…