Miringoplasty is a reconstructive operatif procedure limited to repair timpanic memberane perforation, with mobile ossicular chain, and no pathological tissue in the middle ear cavity. Myringoplasty using lateral graft, the failure cause by reperforation of the tympanic membrane. Mediolateral gfat technique, as a hybrid from medial and lateral technique, could decrease the failure of the myring…
Peptic mucus synthesize especially prostaglandine E2 and I2. Prostaglandine E2 and I2 can impede acid secete and stimulate mucus and bicarbonate secretion. Misoprostol, a synthetic methyl ester analogue of prostaglandin is both a powerful inhibitor of gastric secretion and is able to protect the gastroduodenal mucosa from damage. Misoprostol and other prostaglandine derivatives can be alternati…