Dengue virus infects 50 to 100 million people every year, however, specific treatment or effective antiviral drugs to treat viral infections has not been found yet. Curcumin known has perform the inhibition of ubiquitin-proteasome system that causes a decrease of Japanese encephalitis, one kind of flavivirus. Structural modifications was known to increase the biological activity of curcumin. P…
Virus west nile (WN) dapat menimbulkan penyakit yang ditularkan melalui nyamuk. Di Indonesia virus west nile mulai diperhatikan karena menginfeksi 12 warga Surabaya pada tahun 2014. Pemahaman mengenai virus west nile ditinjau dari aspek epidemiologi, klasifikasi dan dasar molekuler diperlukan untuk mengenal apa dan bagaimana sifat dari virus WN dalam rangka upaya deteksi dini dan pencegahan ter…
Hand, foot, and mouth disease (HFMD) is a common disease caused by human enterovirus (HEV). The symptoms and signs of infection among children typically present with vesicular exanthema on the soles of their feet, the palms of their hands and in their mouths, causing discomfort and feeding difficulties. The disease is caused by mainly Coxsackie virus A16 (CVA16) serotype. It has recently be…
Rabies virus detection using Reverse Transcriptase Polymerase Chain Reaction (RT – PCR) was considered to have high sensitivity and specificity. This method is relatively faster and easy to perform in comparison with other methods such as Fluorescent Antibody Test (FAT) and Mouse Inoculation Test (MIT). Therefore, the RT PCR method is used as ante mortem diagnosis of rabies. A total of 74…
Rotaviruses are the leading cause of gastroenteritis in young children. The incidence of diarrhea due to rotavirus in Indonesia is evenly throughout the year with the mortality approximately of 10,088 children in a year. These viruses are transmitted by fecal-oral route with high rate of transmission. More than 50 combinations G-P known as strain that infect human with the predominant serotypes…
Chikungunya fever is one of re-emerging diseases in Indonesia. The most prominent symptoms in chikungunya patients are severe pain in joints, especially in the knee, ankles, arms and hands joints , as well as joints of the spine so that the joints very difficult to be moved. The disease is caused by Chikungunya virus (CHIKV) group.Cases of Chiku-ngunya in Central Java were increased, starti…