Breast cancer may progress from an atypical lesion. Angiogenesis has an important role in the growth, invasion and metastasis of breast cancer, which can be reflected through the microvascular density (MVD). Tumor associated macrophages (TAMs) are stromal cells that can produce pro-angiogenic factor su ch as vascular endothelial growth factor (VEGF), and induce matrix metalloproteinase-9 (MMP-9…
Having high quality of life is a challenge for school-age children (6-12 years old) who suffer from cancer. They have to undergo cancer treatments that bring pain and negative side-effects for years Repeated hospitalization also separates them from family and school, the essential contexts in school-age children development. By using qualitative approach with interview and observation, this re…
At the meaning associated with a velY varied culture, among others: filling, improving health and healing, prevent iIlness, expressing concem for others, strengthen social ties, the expression of thanks or appreciation, wealth or social status. The purpose of this study was to determine the meaning of eating according to Javanese culture in cancer patients in the city of Surabaya. The method us…
Anemia merupakan faktor prognostik independen untuk pertahanan hidup pasien kanker. Penurunan kapasitas oksigen pada darah dapat menyebabkan terjadinya kondisi hipoksia pada jaringan kanker . Hipoksia pada jaringan kanker dapat mengaktivasi faktor transkripsi hypoxia-inducible factor-1α (HIF-1α) yang kemudian akan mentranskripsi banyak gen lain yang terlibat dalam invasi sel, angiogenesis, me…
Background: Nasopharyngeal carcinoma (NPC) is a multifactorial genetic disease, characteristically endemic and shows considerable differences in its geographical distribution. Besides infection with EBV, genetic factors such as polymorphisms of TCR-β gene contribute to the incidence of NPC. This study investigates the association of TCR-β gene polymorphisms with individual susceptibility to d…