Muscle relaxants have two ways in their working. First, the muscle relaxant which worked in peripher (e.g.: dantrolen), and second, the muscle relaxant which worked in central (e.g.: diazepam, baclofen, carisoprodole, and Tizamidine). This article reviewed about tizanidine as muscle relaxant which worked centrally. This drugs especially worked in medulla spinalis. It was derived to imidazoline …
The Indonesia people still empirically use medicinal plants to overcome their diseases or maintain their health. One of the medicinal plants is Cassia siamea lamk (daun johar) used for treatment of fevers/ malaria and jaundice/hepatitis. A lot of people usually use it for long periods of time. It is preferable for medicinal plants to have no effect rather than toxic effects. Subchronic toxicity…
A study of the effect of wild tamarind (Leucaena leucocephala) leafs extract on clinical symptoms and histological changes in liver of mice (Mus musculus) was conducting in the laboratory. Each of four equal groups of mice was individually fed with an artificial diet, impregnated with the leaf extract, at doses of 0 percent (control), 20 percent, 40 percent and 60 percent w/w on daily basis. Da…