More than 40% of the world's population who live in tropical and subtropical regions at risk for dengue infection. Specific and effective antiviral therapies to treat dengue infection has not been found yet. Many researches proved that curcumin has preventive activity againts viruses, such as vasicular stomatis (VSV), HSV 1 and 2, parainfluenza-3, reovirus-1, feline corona virus, feline herpes …