Chronic Obstructive Pulmonary Diseases (COPD) pervelence in the elderly is incresing. During aging, lung structure and function deteriorate and increase pathogenetic susceptibility to COPD. Aging is a progressive decline of homeostasis that occus after the reproductive phase of life is complete and leading to an increasing risk of disease of death. Failure of organs to repair DNA damage by oxid…
This was a comparative, 2-arm, parallel, randomized, double-blind, placebo-controlled study consisting of a 12-week treatment period aimed to evaluate the efficacy and safety of topical adapa-lene 0.1% cream as an anti-aging therapy. Each enrolled subjects were given both adapalene and place¬bo (vehicle) cream, each of which to be applied on either hand based on the randomly allocated num¬ber…