Dengue virus infects 50 to 100 million people every year, however, specific treatment or effective antiviral drugs to treat viral infections has not been found yet. Curcumin known has perform the inhibition of ubiquitin-proteasome system that causes a decrease of Japanese encephalitis, one kind of flavivirus. Structural modifications was known to increase the biological activity of curcumin. P…
To confirm the presence of any dengue viral in a mosquito, mosquito's head can be squashed on a slide and stained with immunohistochemical staining. The remaining samples then can be stored in the cryo freezer at -80oC to avoid specimen damage. However, for laboratories with limited facilities, with only a refrigerator with a temperature range of -20oC to 4°C is available, examination to evalu…
Dengue infection has expanded to other geographic areas in Indonesia due to changes in human ecology and behavior. I many tropical and subtropical areas of the world this viruses are endemic and causes periodic or annual outbreaks of disease. Among the complex and multifactors responsible for the increase of dengue cases, the transovarian mechanism may play an important role. This research was …