The Role of SHOX Gene in Short Stature of Turner Syndrome and Its Variant

SHOX gene is located on the edge of each short/p arm sex chromosome called the pseudoautosomal region-1 (PARI) plays as a dindomental role on controling chondrocyte differentation and apoptosis in the growth plate. Longitudinal growth is determined by environmental, hormonal and genetic factors. Short stature is defiened as a stature is defined as a standing height below the third percentile ac…

Sindrom Turner

Turner syndrome is a congenital disorder, due to partial or total loss of X chromosome (45, XO). The defmitive etiology is unknown. The incidence is 2.5- 5.5 per 10.000 female live birth. Diagnosis could be established since intrauterine period to birth. The intrauterine diagnosis could be established by applying USG, amniocentesis, and by measuring the alpha feto protein level.'-4 At birth, di…

Sindrom Turner

Edisi

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ISBN/ISSN

0216-4752

Deskripsi Fisik

4p.

Judul Seri

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No. Panggil

Majalah fk. Universitas Kristen Indonesia;27(1)201