Allergic disease including allergic rhinitis (AR) is domited by Th₂responses with increased production of IL-4 and inhibition of IFN-ϒ production BCG vaccination induced IL-12 production which promotes. Th₀ to Th₁ shift and stimulates IFN-ϒ production. The aim of this study is to determine whether BCG vaccination prior specific immunotherapy (SIT) could increase initial phase of SIT re…
Objectives to evaluate the efficacy and the adverse effects of Loradine and Astemizole once daily dose for 14 days treatment, especially to see whether Loratadine is faster than Astemizole in terms of relieving perennial allergic rhinitis symptoms. Study design: Rondomized, double blind clinical trial. Methodology: 65 perennial allergic rhinitis who fulfilled the eligibility criteria were rondo…
The efficacy and safety of loratadine pseudoephedrine sulfate was compared with carbinoxamine maleate phenylephrine HCI in a single blind study in the treatment of 77 patients with allergic rhinitis. The gradation were moderate and severe (the minimal score was 6 for nasal symptoms). Treatment were administered orally twice daily for 14 days and were evaluated at baseline and on days 4, 8 and 1…
Allergic rhinitis is a common diseases encountered by ENT specialist as well as general practitioner. Allergic rhinitis can be treated by allergen avoidance, immunotherapy, food neutralizing treatment, surgical intervention or symptomatic treatment. At present there are several combination of HI-antagonist, which do not easily penetrate the blood brain barrier such as laratadine pseudoephedrine…