Hyperthyroidism is a metabolic imbalance resulting from excessive production of thyroid hormones. Overt or subclinical hyperthyroid prevalence has reached 20%. The differences in thyroid status induce apoptosis in adult cerebral cortex. Triiodothyroxine (T3) acts directly on the cerebral cortex mitochondria and induces the release of cytochrome-c which leads to apoptosis. The increase of hormon…