Calprotectin, a major cytosolic of lekocytes, is detected in neutrophils and monocytes/machrophages. This protein is known to be a marker for several inflamatory disease including periodontitis. In type 2 diabetea mellitus patients, the severity of periodontitis strongly thought caused decreasing of leukocytes fanction such as neutrophluls. Previous research found that the calprotectin level in…