BACKGROUND: Various products used in cellular therapy utilize tissue culture techniques requiring keratinocyte culture. An efficient and clinically acceptable keratinocyte culture system requires supplernents with mitogenic activity. Geraniin is a phytochemical with the potential as a supplement for expansion culture of keratinocytes. The objective of the present study was to verify the mitoge…
Corpus luteum is a transient endocrine gland and its presence plays pivotal role in ovulation process, implantation, and luteinization.The regression of corpus luteum or luteolysis is actually ne eded for next cycle survival and playing a role in roviding new follicles. Luteal regression represents a broad definition of the rocess of demise of the corpus luteum that is capable of accommodatin…
The present study was conducted to investigate the role of curcurnin analogue Pentagamavunone-O (PGV-O) of luteal cell function in apoptosis by examined Bcl-2 and Bax protein expressions. Corpora lutea of rat Sprague-Dawley at 28 days of age after induced by 10 IU pregnant mare's serum gonadotropin (PMSG) were dispersed enzimatically by collagenase. Isolated luteal cells were seeded in 24 well …