ABSTRACT Previous studies showed that tuberculosis vaccine induced a cellular immune response of 38-kDa M tuberculosis hemaggiutinin protein which was found in mice enterocytes. It can induce S-IgA secretion into the intestinal lumen and bronchiolus. It is known that the ISCOM is on effective adjuvantenhances the immune response. interferon(IFItexpression mainly occur…
Peran CD4 CD25 Foxp3 dan TGF-β dalam remodeling saluran napas masih didapatkan kontroversi dan perlu diteliti lebih lanjut. Tujuan dari penelitian ini adalah membuktikan efek meningkatnya jumlah limfosit T Reg CD4 CD25 Foxp3 dan TGF-β terhadap penurunan remodeling saluran napas bronkial paru pada model mencit asma. Mencit Balb/c dibagi menjadi 2 kelompok, yaitu dengan sensitisasi oval…
Histology expression in asthma show inflammatory processes and airway structural changes. Treatment development in asthma needs appropriate animal models but most animal models use short term allergen exposure. The aim of this research was to create an allergic mouse model with allergic inflammation and structureal changes histology expression. Eight female BALB/c mice, 6-12 weeks old, 80-100 g…
Nutrition plays an important role in the incidence of atopic both in children and adults. Several recent guidelines recommended a delay of solid foods to prevent atopic disease. However, until now, there is still much controversy about the influence a delay of solid foods in children to develop atopic disease. This study aimed to determine the impact of the start time of solid foods to atopic c…