Ovalbumin is known as mast cell deranulatin agent through the FC€/RI aggregation. Carboxymethyl chitosan (CMC5), a biocompatible cationic polymer was evaluated to reduces mast cell degranulation induced by ovalbumin. In this experiment, Wistar rats were devided into 5 groups which consist of 1 control group and 4 allergen groups> Among the allergen group, 3 group were trated with carboxymethy…
Histology expression in asthma show inflammatory processes and airway structural changes. Treatment development in asthma needs appropriate animal models but most animal models use short term allergen exposure. The aim of this research was to create an allergic mouse model with allergic inflammation and structureal changes histology expression. Eight female BALB/c mice, 6-12 weeks old, 80-100 g…